TMPRSS3 anticorps

N° du produit ABIN1109275

Cet anticorps Lapin Polyclonal détecte spécifiquement TMPRSS3 dans WB, EIA et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour TMPRSS3 anticorps (ABIN1109275)

Antigène: TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMPRSS3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-TMPRSS3 anticorps

Specificité: This antibody reacts with 49 kDa TMPRSS3 protein.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Antigen Affinity Chromatography

Immunogène: A 15 residue synthetic peptide derived from specific domain of Human TMPRSS3 protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: 0.1 M Tris, 0.1 M Glycine, 50 % Glycerol ( pH 7.8), 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store antibody (in aliquots) at -20 °C.

Détails sur TMPRSS3

Antigène: TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

Autre désignation: TMPRSS3

Sujet: TMPRSS3 is a 437 amno acid membrane bound serine protease and a member of the S1 peptidase family. TMPRSS3 contains an amino-terminal signalanchor sequence and a glycosylated extracellular region containing the serine protease domain. Two novel missense mutations of TMPRSS3, W251C and P404L, alter the highly conserved amino acids of the serine protease domain. TMPRSS3 is expressed in many tissues, including fetal cochle,a a subset of pancreatic cancer and various other cancer tissues. TMPRSS3 is also overexpressed in cancer, suggesting that it may be important for processes in metastasis formation and tumor invasion.Synonyms: ECHOS1, TADG-12, TADG12, Transmembrane protease serine 3, Tumor-associated differentially-expressed gene 12 protein

ID gène: 64699

NCBI Accession: NP_076927

Pathways: Sensory Perception of Sound